Early allograft dysfunction after liver transplantation: an intermediate outcome measure for targeted improvements

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Early allograft dysfunction after liver transplantation: an intermediate outcome measure for targeted improvements.

BACKGROUND The term early allograft dysfunction (EAD) identifies liver transplant (LT) allografts with initial poor function and portends poor allograft and patient survival. Aims of this study are to use EAD as an intermediate outcome measure in a large single center cohort and identify donor, recipient and peri-operative risk factors. MATERIAL AND METHODS In 1950 consecutive primary LT, don...

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Immediate Postoperative Low Platelet Counts After Living Donor Liver Transplantation Predict Early Allograft Dysfunction

To investigate whether the platelets can improve liver function by mediating liver regeneration. Using a retrospective cohort with 234 consecutive adult-to-adult living donor liver transplantation recipients, we have discussed the relationship between immediate postoperative platelet count and outcome. Patients have been stratified into Low Platelet Group (106 patients) with platelet ≤68 × 10/L...

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A proposal to grade the severity of early allograft dysfunction after liver transplantation

OBJECTIVE To propose a grading system for early hepatic graft dysfunction. METHODS A retrospective study from a single transplant center. Recipients of liver transplants from deceased donors, transplanted under the MELD system were included. Early graft dysfunction was defined by Olthoff criteria. Multiple cut-off points of post-transplant laboratory tests were used to create a grading system...

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Outcome after Liver Transplantation for Cystic Fibrosis.

Im~rovements in l'ulmonary care and other refinements in management allow more patients WIth cystic fibroSIS (CF) to survive long enough for liver disease to become a limiting factor in their life expectancy (1, 2, 3). Since liver transplantation is considered the treatment of choice for patients with end-stage liver disease, it is predictable that more patients with CF and liver failure will b...

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ژورنال

عنوان ژورنال: Annals of Hepatology

سال: 2016

ISSN: 1665-2681

DOI: 10.5604/16652681.1184212